Your one stop Vaccination Clinic

Typhoid Vaccine

Typhoid Vaccine

We provide a full range of travel vaccinations and medication

Typhoid

Typhoid fever is a serious bacterial infection caused by the ingestion of food or water contaminated with Salmonella enterica serotype Typhi. It is typically associated with poor sanitation and hygiene practices, particularly in areas where access to clean drinking water is limited. A related illness, paratyphoid fever, is caused by Salmonella paratyphi and presents with similar symptoms, though it is generally less severe. Both infections can lead to high fever, abdominal pain, weakness, and in some cases, serious complications such as intestinal perforation if left untreated. While the vast majority of cases occur in South and Southeast Asia, typhoid and paratyphoid fever are still reported in other parts of the world, particularly in sub-Saharan Africa, and in Central and South America. Travellers to these regions, especially those staying in rural areas or with local communities, should take precautions with food and water and consider vaccination to reduce their risk.

Vaccination Pricing

£40 Per dose
£40 Per Course

Signs & Symptoms

Symptoms of typhoid and paratyphoid include:

  • Fever

  • Headache

  • Muscle or joint pains

  • Constipation or diarrhoea

  • Rash

  • Complications include intestinal bleeding and perforation

Evans Pharmacy & Travel Clinic

General Contact & Travel Vaccination

Tel: 01684 575 216

Email: malverntravelclinic@raylane.co.uk

malverntravelclinic@raylane.co.uk

231 Worcester Road, Malvern, WR14 1SU

Claines Pharmacy & Travel Clinic

General Contact & Travel Vaccination

Tel: 01905 453 703

Email: worcestertravelclinic@raylane.co.uk

worcesterravelclinic@raylane.co.uk

153 Ombersley Road, Worcester, WR3 7BX

The Vaccination – Typhoid injection

Ages (Years) Doses Required Schedule Time before travel Boost required at
2 – 85 1 – 7 – 10 days 3 years

The Vaccination – Oral Typhoid

Ages (Years) Doses Required Schedule Time before travel Boost required at
6 – 85 1 0 ,2, 4 days 10 days See specialist pharmacist

Hepatits A & Typhoid Combined vaccine

Ages (Years) Doses Required Schedule Time before travel Boost required at
16 – 85 1 – 1 – 2 weeks preferably but anytime ok* Hep A booster only given at 6-12 months after 1st dose

*The vaccine will be at its most effective if it’s given time to become active. Some immunity will be provided if you get it up to the day before travel.

Typhoid fever is a potentially serious bacterial infection caused by Salmonella enterica serotype Typhi. It primarily affects the intestinal tract and bloodstream and is transmitted through ingestion of contaminated food or water. A related but usually less severe illness, paratyphoid fever, is caused by Salmonella Paratyphi. Without prompt treatment, typhoid can lead to severe complications, including intestinal perforation and systemic infection. Although rare in the UK due to high hygiene standards and safe water supply, typhoid remains a significant public health concern in many parts of the world, particularly in regions where access to clean water and proper sanitation is limited. Vaccination and strict hygiene practices are the most effective ways to reduce the risk of infection, especially for travellers.

 Typhoid is spread through the faecal-oral route, typically by consuming food or water that has been contaminated with the faeces of an infected person. It is especially prevalent in areas where sanitation is poor, and clean water is not widely available. Prevention relies on a combination of vaccination and practising good hygiene. Travellers to high-risk regions should take care to drink only bottled or purified water, avoid ice in drinks, and eat only thoroughly cooked foods. Hand hygiene is equally important—regular hand washing or use of alcohol-based sanitisers can reduce the risk of ingesting the bacteria. While vaccination does not provide complete protection, it significantly reduces the risk of infection and is strongly recommended for those visiting endemic areas.

There are two types of typhoid vaccines commonly used in the UK: an injectable inactivated vaccine and an oral live-attenuated vaccine. The injectable vaccine is given as a single dose and offers protection for about three years. The oral vaccine, which involves taking capsules over several days, provides protection for approximately five years. The injectable vaccine is more commonly used for short-term travel, especially when time is limited before departure. Neither vaccine offers 100% protection, so it remains essential to follow food and water safety precautions even if vaccinated. Booster doses may be required if you are travelling again after the protection period has lapsed or if you are regularly exposed to risk due to occupation or frequent travel.

Symptoms of typhoid fever typically develop within one to three weeks after exposure. The illness often begins gradually, starting with a rising fever, headache, and general malaise. As it progresses, more specific symptoms may develop, such as abdominal pain, constipation or diarrhoea, loss of appetite, weakness, and a dry cough. In some cases, a rose-coloured rash may appear on the chest or abdomen. If left untreated, typhoid can become more severe, leading to confusion, delirium, intestinal bleeding, or perforation, which can be life-threatening. Prompt antibiotic treatment is usually effective and leads to a full recovery, but resistance to some antibiotics is becoming more common, particularly in South Asia.

Typhoid vaccination is recommended for travellers visiting regions where the disease is endemic and where access to clean water and proper sanitation is limited. High-risk areas include South Asia, particularly India, Pakistan, Bangladesh, and Nepal, as well as parts of Africa, Southeast Asia, Central and South America, and the Middle East. The risk is especially elevated for those staying in rural areas, visiting friends and relatives, or planning extended trips. People working in medical, aid, or humanitarian roles may also be at increased risk. Vaccination may also be required for entry into certain countries depending on the traveller’s previous destinations, particularly if arriving from a high-risk region.

The typhoid vaccine is generally safe and well tolerated, with most side effects being mild and short-lived. The injectable vaccine may cause some redness, swelling, or soreness at the injection site, and occasionally people experience a mild fever, headache, or nausea. The oral vaccine can sometimes cause mild gastrointestinal upset. Serious side effects are very rare, but anyone with known allergies or a weakened immune system should discuss this with a healthcare professional before receiving the vaccine. Although no vaccine offers complete protection, the typhoid vaccine significantly reduces the risk of illness and is an important measure for safe and healthy travel.

Use the map below to identify areas of risk for travel.

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The Malvern Travel Clinic offers a wide range of vaccines and travel vaccinations.

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Competitive Pricing

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